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In recent decades, metals have been considered promising materials in the fields of regenerative medicine and tissue engineering. Metallic bio-materials with excellent mechanical strength can effectively support and replace damaged tissue. Hence, metals have been widely used in load-bearing applications for dentistry and orthopedics. Cobalt-, iron-, and titanium (Ti)-based alloys are representative bio-metals, which are used in various forms, such as vascular stents, hip joints, dental, and orthopedic implants. However, the alloying elements of Co- and Fe-based alloys, Co, Ni, and Cr, induce severe toxicity when ionized in the body, which limits their clinical use. However, Ti and its alloys have been widely used as medical devices and implants, with dental and orthopedic applications due to their excellent bone-regeneration ability, mechanical properties, and corrosion resistance. Even though Ti and its alloys have generally been used for biomedical applications, there are still challenges that must be met to satisfy their clinical application. For example, osseointegration with the surrounding bone tissue at the initial stage of implantation has been pointed to as a major issue. This Special Issue, “Titanium and Its Alloys for Biomedical Applications”, has been proposed to present recent developments in biomedical applications. The nine research articles included in this Special Issue cover broad aspects of Ti-based alloys and composites with respect to their composition, mechanical, and biological properties, as highlighted in this editorial.

Technology: general issues --- History of engineering & technology --- Mining technology & engineering --- metal–matrix composites --- titanium alloy design --- microstructures --- mechanical properties --- biocomposites --- powder metallurgy --- high power impulse magnetron sputtering --- zinc oxide --- tantalum oxide --- thin film --- plasma electrolytic oxidation --- antibacterial --- biocompatibility --- ultraprecision magnetic abrasive finishing (UPMAF) --- environmentally friendly oil --- Ni-Ti stent wire --- surface roughness (Ra) --- removed diameter (RD) --- Ti alloys --- martensitic transformation --- recoverable strain --- synchrotron X-ray diffraction --- Ti6Al4V --- centrifugal casting --- ion implantation --- human osteoblast --- grade V titanium --- mini transitional implants --- narrow diameter implant --- backscattered electrons --- Ti-based biomaterials --- toxicity --- β-phase --- ω-phase --- CALPHAD --- artificial intelligence --- deep learning artificial neural network (DLANN) --- self-organizing maps (SOM) --- titanium --- surface treatment --- HA blasting --- sandblasted and acid-etched (SLA) --- anodic oxidation (AO) --- micro-arc oxidation (MAO) --- graphene oxide --- electrophoretic deposition --- implant --- biomolecule --- complex --- n/a --- metal-matrix composites

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

In recent decades, metals have been considered promising materials in the fields of regenerative medicine and tissue engineering. Metallic bio-materials with excellent mechanical strength can effectively support and replace damaged tissue. Hence, metals have been widely used in load-bearing applications for dentistry and orthopedics. Cobalt-, iron-, and titanium (Ti)-based alloys are representative bio-metals, which are used in various forms, such as vascular stents, hip joints, dental, and orthopedic implants. However, the alloying elements of Co- and Fe-based alloys, Co, Ni, and Cr, induce severe toxicity when ionized in the body, which limits their clinical use. However, Ti and its alloys have been widely used as medical devices and implants, with dental and orthopedic applications due to their excellent bone-regeneration ability, mechanical properties, and corrosion resistance. Even though Ti and its alloys have generally been used for biomedical applications, there are still challenges that must be met to satisfy their clinical application. For example, osseointegration with the surrounding bone tissue at the initial stage of implantation has been pointed to as a major issue. This Special Issue, “Titanium and Its Alloys for Biomedical Applications”, has been proposed to present recent developments in biomedical applications. The nine research articles included in this Special Issue cover broad aspects of Ti-based alloys and composites with respect to their composition, mechanical, and biological properties, as highlighted in this editorial.

metal–matrix composites --- titanium alloy design --- microstructures --- mechanical properties --- biocomposites --- powder metallurgy --- high power impulse magnetron sputtering --- zinc oxide --- tantalum oxide --- thin film --- plasma electrolytic oxidation --- antibacterial --- biocompatibility --- ultraprecision magnetic abrasive finishing (UPMAF) --- environmentally friendly oil --- Ni-Ti stent wire --- surface roughness (Ra) --- removed diameter (RD) --- Ti alloys --- martensitic transformation --- recoverable strain --- synchrotron X-ray diffraction --- Ti6Al4V --- centrifugal casting --- ion implantation --- human osteoblast --- grade V titanium --- mini transitional implants --- narrow diameter implant --- backscattered electrons --- Ti-based biomaterials --- toxicity --- β-phase --- ω-phase --- CALPHAD --- artificial intelligence --- deep learning artificial neural network (DLANN) --- self-organizing maps (SOM) --- titanium --- surface treatment --- HA blasting --- sandblasted and acid-etched (SLA) --- anodic oxidation (AO) --- micro-arc oxidation (MAO) --- graphene oxide --- electrophoretic deposition --- implant --- biomolecule --- complex --- n/a --- metal-matrix composites